Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines

Chem Res Toxicol. 1998 Jun;11(6):559-603. doi: 10.1021/tx980005y.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Carcinogens / toxicity*
  • DNA Adducts / metabolism
  • DNA Damage
  • Genes, p53
  • Genes, ras
  • Hemoglobins / metabolism
  • Humans
  • Lung Neoplasms / chemically induced
  • Mutation
  • Nitrosamines / metabolism
  • Nitrosamines / toxicity*

Substances

  • Carcinogens
  • DNA Adducts
  • Hemoglobins
  • Nitrosamines
  • 4-(methylnitrosoamino)-4-(3-pyridyl)-1-butanol
  • 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
  • N'-nitrosonornicotine