Context Antidepressant medications represent the best established treatment for major
depressive disorder, but there is little evidence that they have a specific pharmacological …

Damage to the central nervous system (CNS) results in a glial reaction, leading eventually to
the formation of a glial scar. In this environment, axon regeneration fails, and remyelination …

Abstract The International Campaign for Cures of Spinal Cord Injury Paralysis (ICCP)
supported an international panel tasked with reviewing the methodology for clinical trials in …

A method is described for the determination of urea in plasma and urine. The effects of
variations in the experimental conditions are examined and the results of recovery …

Background Patients with chronic forms of major depression are difficult to treat, and the
relative efficacy of medications and psychotherapy is uncertain. Methods We randomly …

The inability of axons to regenerate after a spinal cord injury in the adult mammalian central
nervous system (CNS) can lead to permanent paralysis. At sites of CNS injury, a glial scar …

We report a high-quality draft genome sequence of the domesticated apple (Malus×
domestica). We show that a relatively recent (> 50 million years ago) genome-wide …

We report the draft genome sequence of the model moss Physcomitrella patens and
compare its features with those of flowering plants, from which it is separated by more than …

Background Worldwide, grapes and their derived products have a large market. The
cultivated grape species Vitis vinifera has potential to become a model for fruit trees …

The spider mite Tetranychus urticae is a cosmopolitan agricultural pest with an extensive
host plant range and an extreme record of pesticide resistance. Here we present the …