The acute respiratory distress syndrome

LB Ware, MA Matthay - New England Journal of Medicine, 2000 - Mass Medical Soc
The acute respiratory distress syndrome is a common, devastating clinical syndrome of
acute lung injury that affects both medical and surgical patients. Since the last review of this …

[HTML][HTML] The acute respiratory distress syndrome

MA Matthay, LB Ware… - The Journal of clinical …, 2012 - Am Soc Clin Investig
The acute respiratory distress syndrome (ARDS) is an important cause of acute respiratory
failure that is often associated with multiple organ failure. Several clinical disorders can …

[HTML][HTML] Acute respiratory distress syndrome

MA Matthay, RL Zemans, GA Zimmerman… - Nature reviews Disease …, 2019 - nature.com
The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

An expanded definition of the adult respiratory distress syndrome

JF Murray, MA Matthay, JM Luce, MR Flick - Am Rev Respir Dis, 1988 - atsjournals.org
More than twenty years ago, Ashbaugh and coworkers,(1), in a now classic article,
described. 12 patients whose striking but uniform clinical, physiologic, roentgenographic …

An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals

G Matute-Bello, G Downey, BB Moore… - American journal of …, 2011 - atsjournals.org
Acute lung injury (ALI) is well defined in humans, but there is no agreement as to the main
features of acute lung injury in animal models. A Committee was organized to determine the …

The acute respiratory distress syndrome: pathogenesis and treatment

MA Matthay, RL Zemans - Annual Review of Pathology …, 2011 - annualreviews.org
The acute respiratory distress syndrome (ARDS) causes 40% mortality in approximately
200,000 critically ill patients annually in the United States. ARDS is caused by protein-rich …

Acute traumatic coagulopathy: initiated by hypoperfusion: modulated through the protein C pathway?

K Brohi, MJ Cohen, MT Ganter, MA Matthay… - Annals of …, 2007 - journals.lww.com
Objectives: Coagulopathy following major trauma is conventionally attributed to activation
and consumption of coagulation factors. Recent studies have identified an acute …

Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials

CS Calfee, K Delucchi, PE Parsons… - The Lancet …, 2014 - thelancet.com
Background Subphenotypes have been identified within heterogeneous diseases such as
asthma and breast cancer, with important therapeutic implications. We assessed whether …

Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice

N Gupta, X Su, B Popov, JW Lee, V Serikov… - The Journal of …, 2007 - journals.aai.org
Recent in vivo and in vitro work suggests that mesenchymal stem cells (MSC) have anti-
inflammatory properties. In this study, we tested the effect of administering MSC directly into …

The American–European Consensus Conference on ARDS, part 2: ventilatory, pharmacologic, supportive therapy, study design strategies, and issues related to …

A Artigas, GR Bernard, J Carlet, D Dreyfuss… - American journal of …, 1998 - atsjournals.org
The acute respiratory distress syndrome (ARDS) continues as a contributor to the morbidity
and mortality of patients in intensive care units throughout the world, imparting tremendous …