User profiles for "author:Pedro Aguiar"

Pedro MQ Aguiar

Institute for Systems and Robotics (ISR/IST), LARSyS, Instituto Superior Técnico, Univ …
Verified email at isr.ist.utl.pt
Cited by 5299

PD-L1 expression as a predictive biomarker in advanced non-small-cell lung cancer: updated survival data

PN Aguiar Jr, RA De Mello, P Hall, H Tadokoro… - …, 2017 - Future Medicine
Aim: The treatment of non-small-cell lung cancer has changed after the development of the
immune checkpoint inhibitors. Although the most studied biomarker is PD-L1 expression, its …

The role of PD-L1 expression as a predictive biomarker in advanced non-small-cell lung cancer: a network meta-analysis

PN Aguiar Jr, IL Santoro, H Tadokoro… - …, 2016 - Future Medicine
Background: Tumor programmed death ligand one (PD-L1) expression has been studied in
several trials in non-small-cell lung cancer. Methods: We assessed the potential role of PD …

D-ADMM: A communication-efficient distributed algorithm for separable optimization

JFC Mota, JMF Xavier, PMQ Aguiar… - IEEE Transactions on …, 2013 - ieeexplore.ieee.org
We propose a distributed algorithm, named Distributed Alternating Direction Method of
Multipliers (D-ADMM), for solving separable optimization problems in networks of …

Comparative effectiveness of immune-checkpoint inhibitors for previously treated advanced non-small cell lung cancer–a systematic review and network meta …

P San Tan, P Aguiar Jr, B Haaland, G Lopes - Lung Cancer, 2018 - Elsevier
Abstract Introduction Role of PD-L1 expression to guide immunotherapies in previously
treated advanced NSCLC remains unclear and there is a lack of data comparing immune …

Distributed basis pursuit

JFC Mota, JMF Xavier, PMQ Aguiar… - IEEE Transactions on …, 2011 - ieeexplore.ieee.org
We propose a distributed algorithm for solving the optimization problem Basis Pursuit (BP).
BP finds the least ℓ 1-norm solution of the underdetermined linear system Ax= b and is used …

[HTML][HTML] NAD+ analog reveals PARP-1 substrate-blocking mechanism and allosteric communication from catalytic center to DNA-binding domains

MF Langelier, L Zandarashvili, PM Aguiar… - Nature …, 2018 - nature.com
PARP-1 cleaves NAD+ and transfers the resulting ADP-ribose moiety onto target proteins
and onto subsequent polymers of ADP-ribose. An allosteric network connects PARP-1 multi …

[HTML][HTML] The association between chronic disease and serious COVID-19 outcomes and its influence on risk perception: survey study and database analysis

PA Laires, S Dias, A Gama, M Moniz… - JMIR public health …, 2021 - publichealth.jmir.org
Background: COVID-19, a viral respiratory disease first reported in December 2019, quickly
became a threat to global public health. Further understanding of the epidemiology of the …

[PDF][PDF] Turbo parsers: Dependency parsing by approximate variational inference

AFT Martins, NA Smith, E Xing, P Aguiar… - Proceedings of the …, 2010 - aclanthology.org
We present a unified view of two state-of-theart non-projective dependency parsers, both
approximate: the loopy belief propagation parser of Smith and Eisner (2008) and the relaxed …

Cost-effectiveness of osimertinib in the first-line treatment of patients with EGFR-mutated advanced non–small cell lung cancer

PN Aguiar, B Haaland, W Park, P San Tan… - JAMA …, 2018 - jamanetwork.com
Importance The survival of patients with advanced non–small cell lung cancer (NSCLC) with
epidermal growth factor receptor (EGFR) gene mutations has improved substantially in the …

Probing alkali coordination environments in alkali borate glasses by multinuclear magnetic resonance

VK Michaelis, PM Aguiar, S Kroeker - Journal of Non-Crystalline Solids, 2007 - Elsevier
Five series of binary alkali borate glasses were prepared to compare the alkali dependence
of network and modifier short-range order. 11B magic-angle spinning (MAS) NMR reveals …