User profiles for "author:Pedro Aguiar"
Pedro MQ AguiarInstitute for Systems and Robotics (ISR/IST), LARSyS, Instituto Superior Técnico, Univ … Verified email at isr.ist.utl.pt Cited by 5299 |
PD-L1 expression as a predictive biomarker in advanced non-small-cell lung cancer: updated survival data
PN Aguiar Jr, RA De Mello, P Hall, H Tadokoro… - …, 2017 - Future Medicine
Aim: The treatment of non-small-cell lung cancer has changed after the development of the
immune checkpoint inhibitors. Although the most studied biomarker is PD-L1 expression, its …
immune checkpoint inhibitors. Although the most studied biomarker is PD-L1 expression, its …
The role of PD-L1 expression as a predictive biomarker in advanced non-small-cell lung cancer: a network meta-analysis
PN Aguiar Jr, IL Santoro, H Tadokoro… - …, 2016 - Future Medicine
Background: Tumor programmed death ligand one (PD-L1) expression has been studied in
several trials in non-small-cell lung cancer. Methods: We assessed the potential role of PD …
several trials in non-small-cell lung cancer. Methods: We assessed the potential role of PD …
D-ADMM: A communication-efficient distributed algorithm for separable optimization
We propose a distributed algorithm, named Distributed Alternating Direction Method of
Multipliers (D-ADMM), for solving separable optimization problems in networks of …
Multipliers (D-ADMM), for solving separable optimization problems in networks of …
Comparative effectiveness of immune-checkpoint inhibitors for previously treated advanced non-small cell lung cancer–a systematic review and network meta …
Abstract Introduction Role of PD-L1 expression to guide immunotherapies in previously
treated advanced NSCLC remains unclear and there is a lack of data comparing immune …
treated advanced NSCLC remains unclear and there is a lack of data comparing immune …
Distributed basis pursuit
We propose a distributed algorithm for solving the optimization problem Basis Pursuit (BP).
BP finds the least ℓ 1-norm solution of the underdetermined linear system Ax= b and is used …
BP finds the least ℓ 1-norm solution of the underdetermined linear system Ax= b and is used …
[HTML][HTML] NAD+ analog reveals PARP-1 substrate-blocking mechanism and allosteric communication from catalytic center to DNA-binding domains
MF Langelier, L Zandarashvili, PM Aguiar… - Nature …, 2018 - nature.com
PARP-1 cleaves NAD+ and transfers the resulting ADP-ribose moiety onto target proteins
and onto subsequent polymers of ADP-ribose. An allosteric network connects PARP-1 multi …
and onto subsequent polymers of ADP-ribose. An allosteric network connects PARP-1 multi …
[HTML][HTML] The association between chronic disease and serious COVID-19 outcomes and its influence on risk perception: survey study and database analysis
Background: COVID-19, a viral respiratory disease first reported in December 2019, quickly
became a threat to global public health. Further understanding of the epidemiology of the …
became a threat to global public health. Further understanding of the epidemiology of the …
[PDF][PDF] Turbo parsers: Dependency parsing by approximate variational inference
We present a unified view of two state-of-theart non-projective dependency parsers, both
approximate: the loopy belief propagation parser of Smith and Eisner (2008) and the relaxed …
approximate: the loopy belief propagation parser of Smith and Eisner (2008) and the relaxed …
Cost-effectiveness of osimertinib in the first-line treatment of patients with EGFR-mutated advanced non–small cell lung cancer
Importance The survival of patients with advanced non–small cell lung cancer (NSCLC) with
epidermal growth factor receptor (EGFR) gene mutations has improved substantially in the …
epidermal growth factor receptor (EGFR) gene mutations has improved substantially in the …
Probing alkali coordination environments in alkali borate glasses by multinuclear magnetic resonance
VK Michaelis, PM Aguiar, S Kroeker - Journal of Non-Crystalline Solids, 2007 - Elsevier
Five series of binary alkali borate glasses were prepared to compare the alkali dependence
of network and modifier short-range order. 11B magic-angle spinning (MAS) NMR reveals …
of network and modifier short-range order. 11B magic-angle spinning (MAS) NMR reveals …