The potential chemical structure of anti‐SARS‐CoV‐2 RNA‐dependent RNA polymerase
An outbreak of coronavirus disease 2019 (COVID‐19) occurred in Wuhan and it has rapidly
spread to almost all parts of the world. For coronaviruses, RNA‐dependent RNA polymerase …
spread to almost all parts of the world. For coronaviruses, RNA‐dependent RNA polymerase …
Design and methods of the Population Assessment of Tobacco and Health (PATH) Study
A Hyland, BK Ambrose, KP Conway… - Tobacco …, 2017 - tobaccocontrol.bmj.com
Background This paper describes the methods and conceptual framework for Wave 1 of the
Population Assessment of Tobacco and Health (PATH) Study data collection. The National …
Population Assessment of Tobacco and Health (PATH) Study data collection. The National …
[HTML][HTML] Tobacco-product use by adults and youths in the United States in 2013 and 2014
Background Noncigarette tobacco products are evolving rapidly, with increasing popularity
in the United States. Methods We present prevalence estimates for 12 types of tobacco …
in the United States. Methods We present prevalence estimates for 12 types of tobacco …
[HTML][HTML] Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies
M Traylor, M Farrall, EG Holliday, C Sudlow… - The Lancet …, 2012 - thelancet.com
Background Various genome-wide association studies (GWAS) have been done in
ischaemic stroke, identifying a few loci associated with the disease, but sample sizes have …
ischaemic stroke, identifying a few loci associated with the disease, but sample sizes have …
[HTML][HTML] The influence of age and sex on genetic associations with adult body size and shape: a large-scale genome-wide interaction study
TW Winkler, AE Justice, M Graff, L Barata… - PLoS …, 2015 - journals.plos.org
Genome-wide association studies (GWAS) have identified more than 100 genetic variants
contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI …
contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI …
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke
International Stroke Genetics Consortium (ISGC)… - Nature …, 2012 - nature.com
Genetic factors have been implicated in stroke risk, but few replicated associations have
been reported. We conducted a genome-wide association study (GWAS) for ischemic stroke …
been reported. We conducted a genome-wide association study (GWAS) for ischemic stroke …
[PDF][PDF] Genome analyses of> 200,000 individuals identify 58 loci for chronic inflammation and highlight pathways that link inflammation and complex disorders
S Ligthart, A Vaez, U Võsa, MG Stathopoulou… - The American Journal of …, 2018 - cell.com
C-reactive protein (CRP) is a sensitive biomarker of chronic low-grade inflammation and is
associated with multiple complex diseases. The genetic determinants of chronic …
associated with multiple complex diseases. The genetic determinants of chronic …
Obesity increases risk of ischemic stroke in young adults
AB Mitchell, JW Cole, PF McArdle, YC Cheng, KA Ryan… - Stroke, 2015 - Am Heart Assoc
Background and Purpose—Body mass index has been associated with ischemic stroke in
older populations, but its association with stroke in younger populations is not known. In light …
older populations, but its association with stroke in younger populations is not known. In light …
Common variation in PHACTR1 is associated with susceptibility to cervical artery dissection
S Debette, Y Kamatani, TM Metso, M Kloss… - Nature …, 2015 - nature.com
Cervical artery dissection (CeAD), a mural hematoma in a carotid or vertebral artery, is a
major cause of ischemic stroke in young adults although relatively uncommon in the general …
major cause of ischemic stroke in young adults although relatively uncommon in the general …
Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and …
Carotid intima media thickness (cIMT) and plaque determined by ultrasonography are
established measures of subclinical atherosclerosis that each predicts future cardiovascular …
established measures of subclinical atherosclerosis that each predicts future cardiovascular …